HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation

Venkat Giri Magupalli, Roberto Negro, Yuzi Tian, +16

Science

Bone Marrow Mesenchymal Stem Cells-Derived Exosomal MiR-29b-3p Regulates Aging-Associated Insulin Resistance

Tian Su, Yuzhong Xiao, Ye Xiao, +7

ACS Nano

Adult Stem CellImmunologyExtracellular MicrovesiclesBiomedical EngineeringInsulin Signaling +16

Citrullinated Histone H3 as a Therapeutic Target for Endotoxic Shock in Mice

Qiufang Deng, Baihong Pan, Hasan B. Alam, +9

Frontiers in Immunology

Inhibition of peptidylarginine deiminase alleviates LPS-induced pulmonary dysfunction and improves survival in a mouse model of lethal endotoxemia

Yingjian Liang, Baihong Pan, Hasan B. Alam, +10

European Journal of Pharmacology

InflammationInflammatory Lung DiseasePeptidylarginine DeiminaseMedicineLethal Endotoxemia +10

CitH3: a reliable blood biomarker for diagnosis and treatment of endotoxic shock

Baihong Pan, Hasan B. Alam, Chong Wei, +9

Scientific Reports

Peptidylarginine deiminase 2 has potential as both a biomarker and therapeutic target of sepsis

Yuzi Tian, Shibin Qu, Hasan B. Alam, +13

JCI Insight

Inhibition of PAD2 Improves Survival in a Mouse Model of Lethal LPS-Induced Endotoxic Shock

Zhenyu Wu, Qiufang Deng, Baihong Pan, +7

Inflammation

InflammationSignal TransductionPad2 Improves SurvivalMedicineApoptosis +10

Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice

Ting Zhao, Baihong Pan, Hasan B. Alam, +5

Scientific Reports

An Integrated Plasmo‐Photoelectronic Nanostructure Biosensor Detects an Infection Biomarker Accompanying Cell Death in Neutrophils

Younggeun Park, Byunghoon Ryu, Qiufang Deng, +7

Small

Protective Effect of Tubastatin A in CLP-Induced Lethal Sepsis

Qiufang Deng, Ting C. Zhao, Baihong Pan, +9

Inflammation

Cell DeathSepsisTherapeutic EfficacyPharmacotherapyMedicine +1