VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain

Nicholas van Bruggen, Harold Thibodeaux, James T. Palmer, +8

Journal of Clinical Investigation

ImmunologyCell DeathEdematous Tissue 1Cerebral Vascular RegulationInflammation +22

Evidence for a protective role of metallothionein-1 in focal cerebral ischemia

Menno van Lookeren Campagne, Harold Thibodeaux, Nick van Bruggen, +5

Proceedings of the National Academy of Sciences

Transient Focal IschemiaMetal Binding ProteinsCell DeathFocal Cerebral IschemiaRedox Biology +19

Hematopoietic Stem Cell Maintenance and Differentiation Are Supported by Embryonic Aorta-Gonad-Mesonephros Region–Derived Endothelium

Osamu Ohneda, C Fennie, Zhong Zheng, +5

Blood

Induction of gp91-<i>phox</i>, a Component of the Phagocyte NADPH Oxidase, in Microglial Cells during Central Nervous System Inflammation

Simon P. Green, Belinda Cairns, Julie Rae, +4

Journal of Cerebral Blood Flow & Metabolism

ImmunologyCell DeathReactive Oxygen SpeciesRedox BiologyPhagocyte Nadph Oxidase +22

Increased Binding Activity at an Antioxidant-Responsive Element in the Metallothionein-1 Promoter and Rapid Induction of Metallothionein-1 and -2 in Response to Cerebral Ischemia and Reperfusion

Menno van Lookeren Campagne, Harold Thibodeaux, Nick van Bruggen, +2

Journal of Neuroscience

Rapid InductionTransient Focal IschemiaRedox BiologyOxidative StressCerebral Vascular Regulation +19

Antitumor activity of an anti‐<scp>CD</scp>98 antibody

Gregory M. Hayes, Lawrence Chinn, Joseph M. Cantor, +9

International Journal of Cancer

Antitumor ActivityImmunologyCare CarboplatinImmunotherapeuticsImmunotherapy +15

An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy

Sarah Chan, Nicole A. Belmar, Sun K. Ho, +38

Nature Cancer

Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity

Sun K. Ho, Zhenghai Xu, Archana Thakur, +15

Molecular Cancer Therapeutics

CD39 is a promising therapeutic antibody target for the treatment of soft tissue sarcoma.

Gregory M. Hayes, Belinda Cairns, Zoia Levashova, +8

PubMed

Tumor BiologyCd39 Nucleotidase ActivitySoft Tissue SarcomaMalignant DiseaseImmunology +9

Retinal Gene Expression and Visually Evoked Behavior in Diabetic Long Evans Rats

Stefanie J. Kirwin, Suzanne T. Kanaly, Candice R. Hansen, +3

Investigative Ophthalmology & Visual Science