β-Defensin 2 is a responsive biomarker of IL-17A–driven skin pathology in patients with psoriasis

Frank Kolbinger, Christian Loesche, Marie‐Anne Valentin, +13

Journal of Allergy and Clinical Immunology

Population Pharmacokinetic Modeling of Secukinumab in Patients With Moderate to Severe Psoriasis

Gerard Bruin, Christian Loesche, Judit Nyirady, +1

The Journal of Clinical Pharmacology

InflammationAutoimmune DiseaseMedicineHuman Monoclonal AntibodySevere Psoriasis +13

Comparison of adapalene 0·1% solution and tretinoin 0·025% gel in the topical treatment of acne vulgaris

Charles N. Ellis, Millikan, Smith, +8

British Journal of Dermatology

Lipidomics Profiling of Hidradenitis Suppurativa Skin Lesions Reveals Lipoxygenase Pathway Dysregulation and Accumulation of Proinflammatory Leukotriene B4

Carlos A. Penno, Petra Jäger, Claire Laguerre, +12

Journal of Investigative Dermatology

InflammationAutoimmune DiseaseImmunologyChronic InflammationDermatology +4

Synergistic efficacy of adapalene 0.1%-benzoyl peroxide 2.5% in the treatment of 3855 acne vulgaris patients

Jerry Tan, Harald Gollnick, Christian Loesche, +2

Journal of Dermatological Treatment

Synergistic EfficacyTranslational MedicineMedicineTopical DrugAcne Vulgaris Patients +9

<scp>IL‐17A</scp> is a pertinent therapeutic target for moderate‐to‐severe hidradenitis suppurativa: Combined results from a pre‐clinical and phase <scp>II</scp> proof‐of‐concept study

Alexa B. Kimball, Christian Loesche, Errol P. Prens, +9

Experimental Dermatology

Adapalene gel 0.1% is effective and safe for Japanese patients with acne vulgaris: A randomized, multicenter, investigator-blinded, controlled study

Makoto Kawashima, Shôtarô Harada, Christian Loesche, +1

Journal of Dermatological Science

MedicineAcne VulgarisTopical DrugClinical DermatologyDermatology +3

Randomized controlled trial of the tolerability, safety, and efficacy of adapalene gel 0.1% and tretinoin microsphere gel 0.1% for the treatment of acne vulgaris.

Diane Thiboutot, Michael H. Gold, Michael Jarratt, +6

PubMed

Controlled TrialAdapalene Gel 0.1Acne VulgarisTopical DrugClinical Dermatology +8

Full exome sequencing of 11 families with Hidradenitis suppurativa

Peter Theut Riis, Isabella Loft, Shiva Yazdanyar, +8

Journal of the European Academy of Dermatology and Venereology

Cumulative irritation comparison of adapalene gel and solution with 2 tazarotene gels and 3 tretinoin formulations.

Alan Greenspan, Christian Loesche, Nancy Vendetti, +5

PubMed

Medicinal ChemistryAdapalene Gel 0.1MedicineTretinoin FormulationsTopical Drug +13