Zhengyin Yan

Allometric scaling of pharmacokinetic parameters in drug discovery: Can human CL, Vss and t1/2 be predicted fromin-vivo rat data?

Gary W. Caldwell, John A. Masucci, Zhengyin Yan et al. · European Journal of Drug Metabolism and Pharmacokinetics · 2004 · 145 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Stable-Isotope Trapping and High-Throughput Screenings of Reactive Metabolites Using the Isotope MS Signature

Zhengyin Yan, Gary W. Caldwell · Analytical Chemistry · 2004 · 127 citations

Life Sciences, Biochemistry, Toxicology +17

Highly predictive and interpretable models for PAMPA permeability

Hongmao Sun, Kimloan Nguyen, Edward H. Kerns et al. · Bioorganic & Medicinal Chemistry · 2017 · 114 citations · Full text

Engineering, Chemical Engineering, Transport Phenomena +11

Alternative functional in vitro models of human intestinal epithelia

Amanda L. Kauffman, Alexandra Gyurdieva, John R. Mabus et al. · Frontiers in Pharmacology · 2013 · 109 citations · Full text

Life Sciences, Cell Biology, Pharmacology +15

DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES

Zhengyin Yan, Jian Li, Norman Huebert et al. · Drug Metabolism and Disposition · 2005 · 88 citations

Medicine, Biochemistry, Pharmacology +17