Zhengyin Yan

Allometric scaling of pharmacokinetic parameters in drug discovery: Can human CL, Vss and t1/2 be predicted fromin-vivo rat data?

Gary W. Caldwell, John A. Masucci, Zhengyin Yan et al. · European Journal of Drug Metabolism and Pharmacokinetics · 2004 · 143 citations

Preclinical Drug Evaluation, Medicine, Allometric Scaling +6

Stable-Isotope Trapping and High-Throughput Screenings of Reactive Metabolites Using the Isotope MS Signature

Zhengyin Yan, Gary W. Caldwell · Analytical Chemistry · 2004 · 127 citations

Metabolomic Profiling, Secondary Metabolite, Chemistry +19

Highly predictive and interpretable models for PAMPA permeability

Hongmao Sun, Kimloan Nguyen, Edward H. Kerns et al. · Bioorganic & Medicinal Chemistry · 2017 · 111 citations · Full text

Engineering, Water Resources, Pampa Permeability +5

Alternative functional in vitro models of human intestinal epithelia

Amanda L. Kauffman, Alexandra Gyurdieva, John R. Mabus et al. · Frontiers in Pharmacology · 2013 · 108 citations · Full text

Alternative Functional, Induced Pluripotent Stem Cell, Immunology +10

DETECTION OF A NOVEL REACTIVE METABOLITE OF DICLOFENAC: EVIDENCE FOR CYP2C9-MEDIATED BIOACTIVATION VIA ARENE OXIDES

Zhengyin Yan, Jian Li, Norman Huebert et al. · Drug Metabolism and Disposition · 2005 · 88 citations