Autism-like behaviours with transient histone hyperacetylation in mice treated prenatally with valproic acid

Shunsuke Kataoka, Kazuhiro Takuma, Yuta Hara, +3

The International Journal of Neuropsychopharmacology

Vpa ExposureEpigenetic ChangeEpigeneticsSocial SciencesAutism +14

Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism

Kazuhiro Takuma, Yuta Hara, Shunsuke Kataoka, +8

Pharmacology Biochemistry and Behavior

Valproic AcidBrain FunctionEducationAutismNeuropharmacology +6

Environmental enrichment attenuates behavioral abnormalities in valproic acid-exposed autism model mice

Hiroshi Yamaguchi, Yuta Hara, Yukio Ago, +6

Behavioural Brain Research

Behavioral SciencesPsychiatryBehavioral NeuroscienceMedicineSyndromic Autism +8

Effect of Prenatal Valproic Acid Exposure on Cortical Morphology in Female Mice

Yuta Hara, Yuko Maeda, Shunsuke Kataoka, +3

Journal of Pharmacological Sciences

A Highly Active Form of XCL1/Lymphotactin Functions as an Effective Adjuvant to Recruit Cross-Presenting Dendritic Cells for Induction of Effector and Memory CD8+ T Cells

Kazuhiko Matsuo, Kosuke Kitahata, Fumika Kawabata, +7

Frontiers in Immunology

Oxytocin attenuates deficits in social interaction but not recognition memory in a prenatal valproic acid-induced mouse model of autism

Yuta Hara, Yukio Ago, Momoko Higuchi, +5

Hormones and Behavior

Cognitive ScienceBrain FunctionBehavioral NeuroscienceDevelopmental Cognitive NeuroscienceSyndromic Autism +12

Improvement by methylphenidate and atomoxetine of social interaction deficits and recognition memory impairment in a mouse model of valproic acid‐induced autism

Yuta Hara, Yukio Ago, Atsuki Taruta, +7

Autism Research

Risperidone and aripiprazole alleviate prenatal valproic acid-induced abnormalities in behaviors and dendritic spine density in mice

Yuta Hara, Yukio Ago, Atsuki Taruta, +8

Psychopharmacology

Spinal Cord InjuryMedicineDendritic Spine DensityNeuropharmacologyExperimental Pharmacology +4

Reduced prefrontal dopaminergic activity in valproic acid-treated mouse autism model

Yuta Hara, Kazuhiro Takuma, Erika Takano, +6

Behavioural Brain Research

PsychiatrySyndromic AutismAutismNeuropharmacologyNeuroscience +6

A CCR4 antagonist ameliorates atopic dermatitis-like skin lesions induced by dibutyl phthalate and a hydrogel patch containing ovalbumin

Kazuhiko Matsuo, Shota Hatanaka, Yuta Kimura, +8

Biomedicine & Pharmacotherapy