Seth Sadis

A Ubiquitin Mutant with Specific Defects in DNA Repair and Multiubiquitination

Jean Spence, Seth Sadis, Arthur L. Haas et al. · Molecular and Cellular Biology · 1995 · 545 citations · Full text

Chromatin, Genome Instability, Protein Function +12

The Multiubiquitin-Chain-Binding Protein Mcb1 Is a Component of the 26S Proteasome in <i>Saccharomyces cerevisiae</i> and Plays a Nonessential, Substrate-Specific Role in Protein Turnover

Steve van Nocker, Seth Sadis, David M. Rubin et al. · Molecular and Cellular Biology · 1996 · 387 citations · Full text

Protein Quality Control, Protein Function, Ubiquitin-proteasome Pathway +15

Herpes Simplex Virus Type 1 Immediate-Early Protein ICP0 and Its Isolated RING Finger Domain Act as Ubiquitin E3 Ligases In Vitro

Chris Boutell, Seth Sadis, Roger D. Everett · Journal of Virology · 2002 · 383 citations · Full text

Viral Replication, Viral Pathogenesis, Immunology +20

Phase IIb dose‐ranging study of the oral JAK inhibitor tofacitinib (CP‐690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease‐modifying antirheumatic drugs

Roy Fleischmann, Maurizio Cutolo, Mark C. Genovese et al. · Arthritis & Rheumatism · 2011 · 376 citations

Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.

Daniel Finley, Seth Sadis, Brett P. Monia et al. · Molecular and Cellular Biology · 1994 · 353 citations · Full text

Fungal Cell Biology, Genetics, Proteasome +19