Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal

Naoki Ikenaga, Zhenwei Peng, Kahini A. Vaid, +7

Gut

Lipid Rafts and Caveolin-1 Are Required for Invadopodia Formation and Extracellular Matrix Degradation by Human Breast Cancer Cells

Hideki Yamaguchi, Yukiko Takeo, Shuhei Yoshida, +3

Cancer Research

Proteinlipid InteractionBiochemistryLipid RaftsInvadopodia FormationCell-matrix Interaction +13

Extrahepatic Platelet-Derived Growth Factor-β, Delivered by Platelets, Promotes Activation of Hepatic Stellate Cells and Biliary Fibrosis in Mice

Shuhei Yoshida, Naoki Ikenaga, Susan B. Liu, +9

Gastroenterology

Hepatic Stellate CellsImmunologyFatty Liver DiseaseCholangiopathiesCholangiocyte Biology +16

Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma

Shuhei Yoshida, Miroslaw Kornek, Naoki Ikenaga, +6

Hepatology

Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation

Hideki Yamaguchi, Shuhei Yoshida, Emi Muroi, +6

The Journal of Cell Biology

Pi3k InhibitorsMolecular RegulationCancer BiologyCellular PhysiologyTumor Biology +16

A New Mdr2−/− Mouse Model of Sclerosing Cholangitis with Rapid Fibrosis Progression, Early-Onset Portal Hypertension, and Liver Cancer

Naoki Ikenaga, Susan B. Liu, Deanna Sverdlov, +5

American Journal Of Pathology

ImmunologyGastroenterologyPathologyCholangiopathiesAutoimmune Liver Disease +15

Combined use of percutaneous ethanol injection and radiofrequency ablation for the effective treatment of hepatocelluar carcinoma

Kazutaka Kurokohchi, Sharon Watanabe, Tsutomu Masaki, +6

International Journal of Oncology

Surgical OncologyPathologySurgeryNecrosis AreasCirrhosis +16

Phosphatidylinositol 4,5‐bisphosphate and PIP5‐kinase Iα are required for invadopodia formation in human breast cancer cells

Hideki Yamaguchi, Shuhei Yoshida, Emi Muroi, +5

Cancer Science

Reduced expression of cell cycle regulator p18INK4C in human hepatocellular carcinoma

Asahiro Morishita, Tsutomu Masaki, Hitoshi Yoshiji, +14

Hepatology

GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer

Yuichiro Sawada, Tadahiko Kikugawa, Hiroyuki Iio, +12

International Journal of Cancer

Systems BiologyOncologyHealth SciencesMedicineCell Cycle Regulation +13