Concepedia

Jothilatha Krishnamoorthy

JK

6

Publications

316

Citations

6

H-Index

2015

Active since

Affiliations

McGill University(Current)

Jewish General Hospital

Poznan University of Medical Sciences

McGill University Health Centre

Case Western Reserve University

Jothilatha Krishnamoorthy is an author at McGill University specializing in gene expression, tumor biology, and oxidative stress.

Top concepts

Publications per year

2015–2021

6

Publications

6

Phosphorylation of the translation initiation factor eIF2α at serine 51 determines the cell fate decisions of Akt in response to oxidative stress

Jothilatha Krishnamoorthy, Urszula Kazimierczak, Clara Tenkerian et al. · Cell Death and Disease · 2015 · 104 citations · Full text

The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer

Nour Ghaddar, Shuo Wang, Bethany Woodvine et al. · Nature Communications · 2021 · 73 citations · Full text

An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy

Cédric Darini, Nour Ghaddar, Catherine Chabot et al. · Nature Communications · 2019 · 58 citations · Full text

mTORC2 Balances AKT Activation and eIF2α Serine 51 Phosphorylation to Promote Survival under Stress

Clara Tenkerian, Jothilatha Krishnamoorthy, Zineb Mounir et al. · Molecular Cancer Research · 2015 · 38 citations

The eIF2α serine 51 phosphorylation-ATF4 arm promotes HIPPO signaling and cell death under oxidative stress

Kamindla Rajesh, Jothilatha Krishnamoorthy, Jyotsana Gupta et al. · Oncotarget · 2016 · 31 citations · Full text

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