Mari Ohmichi

Utility of Postcolumn Addition of 2-(2-Methoxyethoxy)ethanol, a Signal-Enhancing Modifier, for Metabolite Screening with Liquid Chromatography and Negative Ion Electrospray Ionization Mass Spectrometry

Jun‐ichi Yamaguchi, Mari Ohmichi, Shigeji Jingu et al. · Analytical Chemistry · 1999 · 27 citations

Postcolumn Addition, Metabolomic Profiling, Signal-enhancing Modifier +18

Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia

Aya Futamura, Ryo Suzuki, Yunoshin Tamura et al. · Bioorganic & Medicinal Chemistry · 2020 · 25 citations · Full text

Sleep, Functional Selectivity, Medicine +7

Discovery and in vitro and in vivo profiles of N-ethyl-N-[2-[3-(5-fluoro-2-pyridinyl)-1H-pyrazol-1-yl]ethyl]-2-(2H-1,2,3-triazol-2-yl)-benzamide as a novel class of dual orexin receptor antagonist

Ryo Suzuki, Dai Nozawa, Aya Futamura et al. · Bioorganic & Medicinal Chemistry · 2015 · 23 citations

Vivo Profiles, Biochemistry, Medicine +6

Development of TASP0410457 (TASP457), a novel dihydroquinolinone derivative as a PET radioligand for central histamine H3 receptors

Kazumi Koga, Jun Maeda, Masaki Tokunaga et al. · EJNMMI Research · 2016 · 16 citations · Full text

Identification of rat urinary and biliary metabolites of esonarimod, a novel antirheumatic drug, using liquid chromatography/electrospray ionization tandem mass spectrometry with postcolumn addition of 2-(2-methoxyethoxy)ethanol, a signal-enhancing modifier.

Jun‐ichi Yamaguchi, Mari Ohmichi, Morifumi Hasegawa et al. · PubMed · 2001 · 12 citations

Pharmaceutical Science, Pharmacotherapy, Aromatic Methyl Group +16