M. O. Wright

Mechanotransduction via integrins and interleukinâ4 results in altered aggrecan and matrix metalloproteinase 3 gene expression in normal, but not osteoarthritic, human articular chondrocytes

S. J. Millward‐Sadler, M. O. Wright, Liza Davies et al. · Arthritis & Rheumatism · 2000 · 232 citations

Life Sciences, Molecular Biology, Orthopaedic Surgery +17

Hyperpolarisation of cultured human chondrocytes following cyclical pressure‐induced strain: Evidence of a role for α5β1 integrin as a chondrocyte mechanoreceptor

M. O. Wright, K. Nishida, Charles D. Bavington et al. · Journal of Orthopaedic Research® · 1997 · 179 citations

Life Sciences, Cell Biology, Physiology +17

Effects of Intermittent Pressure-Induced Strain on the Electrophysiology of Cultured Human Chondrocytes: Evidence for the Presence of Stretch-Activated Membrane Ion Channels

M. O. Wright, Paresh Jobanputra, Charles D. Bavington et al. · Clinical Science · 1996 · 177 citations

Natural Sciences, Cell Biology, Physiology +17

Integrin and Mechanosensitive Ion Channel-Dependent Tyrosine Phosphorylation of Focal Adhesion Proteins and β-Catenin in Human Articular Chondrocytes After Mechanical Stimulation

H. S. Lee, S.J. Millward‐Sadler, M. O. Wright et al. · Journal of Bone and Mineral Research · 2000 · 175 citations · Full text

Life Sciences, Biophysics, Physiology +17

Integrin-regulated Secretion of Interleukin 4: A Novel Pathway of Mechanotransduction in Human Articular Chondrocytes

S.J. Millward‐Sadler, M. O. Wright, H.-S. Lee et al. · The Journal of Cell Biology · 1999 · 175 citations · Full text

Life Sciences, Biophysics, Cell Biology +17