Cysteine protease isoforms from Trypanosoma cruzi, cruzipain 2 and cruzain, present different substrate preference and susceptibility to inhibitors

Ana Paula C. A. Lima, Flavia C. G. Reis, Carole Serveau, +7

Molecular and Biochemical Parasitology

Trypanosoma CruziBiochemistryParasitic ProtozoaNatural SciencesMedicine +6

Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of <i>Trypanosoma cruzi</i>, through the use of cystatin-derived substrates and inhibitors

Carole Serveau, Gilles Lalmanach, María A. Juliano, +3

Biochemical Journal

A comparison of the enzymatic properties of the major cysteine proteinases from Trypanosoma congolense and Trypanosoma cruzi

Jair R. Chagas, Édith Authié, Carole Serveau, +3

Molecular and Biochemical Parasitology

Trypanosoma CruziMajor Cysteine ProteinasesBiochemistryParasitic ProtozoaNatural Sciences +6

Subsite specificity of trypanosomal cathepsin L‐like cysteine proteases

Fabien Lecaille, Édith Authié, Thierry Moreau, +3

European Journal of Biochemistry

Protein ChemistryPhe AnalogsTrypanosoma CruziProtein FunctionBioorganic Chemistry +12

Biotin-labelled peptidyl diazomethane inhibitors derived from the substrate-like sequence of cystatin: targeting of the active site of cruzipain, the major cysteine proteinase of <i>Trypanosoma cruzi</i>

Gilles Lalmanach, Roger Mayer, Carole Serveau, +2

Biochemical Journal

Inhibition of rat tissue kallikrein gene family members by rat kallikrein‐binding protein and α1‐proteinase inhibitor

Carole Serveau, Thierry Moreau, G.X. Zhou, +2

FEBS Letters

InflammationMolecular PharmacologyTissue-kallikrein Family MembersMolecular PhysiologySignal Transduction +13

Functional expression of the catalytic domains of two cysteine proteinases from Trypanosoma congolense

Alain Boulangé, Carole Serveau, M. Brillard, +5

International Journal for Parasitology

Protein FunctionCellular EnzymologyBiochemistryParasitic ProtozoaNatural Sciences +5

Discrimination of cruzipain, the major cysteine proteinase of <i>Trypanosoma cruzi</i>, and mammalian cathepsins B and L, by a pH‐inducible fluorogenic substrate of trypanosomal cysteine proteinases

Carole Serveau, Gilles Lalmanach, Isaura Y. Hirata, +3

European Journal of Biochemistry

New substrates of papain, based on the conserved sequence of natural inhibitors of the cystatin family

Carole Serveau, Luiz Juliano, Pierre Bernard, +3

Biochimie

PhytoalexinBiochemistryMedicineNatural Product BiosynthesisCystatin Family +4

Conserved cystatin segments as models for designing specific substrates and inhibitors of cysteine proteinases

Gilles Lalmanach, Carole Serveau, Michéle Brillard‐Bourdet, +4

Journal of Protein Chemistry

Cellular EnzymologyBiochemistryProtein FoldingNatural SciencesMolecular Biology +9