Gabriela Mladenova

Discovery of<i>cis</i>-<i>N</i>-(1-(4-(Methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: A 1,6-Disubstituted Indoline Derivative as a Highly Selective Inhibitor of Human Neuronal Nitric Oxide Synthase (nNOS) without Any Cardiovascular Liabilities

Subhash C. Annedi, Jailall Ramnauth, Shawn P. Maddaford et al. · Journal of Medicinal Chemistry · 2011 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Design, Synthesis, and Biological Evaluation of 3,4-Dihydroquinolin-2(1<i>H</i>)-one and 1,2,3,4-Tetrahydroquinoline-Based Selective Human Neuronal Nitric Oxide Synthase (nNOS) Inhibitors

Jailall Ramnauth, Joanne Speed, Shawn P. Maddaford et al. · Journal of Medicinal Chemistry · 2011 · 31 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Discovery of<i>N</i>-(3-(1-Methyl-1,2,3,6-tetrahydropyridin-4-yl)-1<i>H</i>-indol-6-yl) thiophene-2-carboximidamide as a Selective Inhibitor of Human Neuronal Nitric Oxide Synthase (nNOS) for the Treatment of Pain

Subhash C. Annedi, Shawn P. Maddaford, Gabriela Mladenova et al. · Journal of Medicinal Chemistry · 2011 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Studies of 9-Fluorenyl Carbocations. Intramolecular Hydride Migration in a Substituted 9-Fluorenyl Carbocation

Gabriela Mladenova, Lie Chen, Chris F. Rodriquez et al. · The Journal of Organic Chemistry · 2001 · 29 citations

Natural Sciences, Chemistry, Chemical Kinetics +12

Discovery of a potent, orally bioavailable and highly selective human neuronal nitric oxide synthase (nNOS) inhibitor, N-(1-(piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide as a pre-clinical development candidate for the treatment of migraine

Subhash C. Annedi, Shawn P. Maddaford, Jailall Ramnauth et al. · European Journal of Medicinal Chemistry · 2012 · 22 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7