Concepedia

Steven P. Govek

SP

Statistics

Publications

10

Citations

937

H-Index

10

Active since

1998

Affiliations

Edison Pharmaceuticals (United States)(Current)

University of California, Irvine

Steven P. Govek is an author at Edison Pharmaceuticals (United States) specializing in medicine, pharmacology, and drug discovery.

Publications per year

1998–2018

10

Publications

10

Identification of GDC-0810 (ARN-810), an Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) that Demonstrates Robust Activity in Tamoxifen-Resistant Breast Cancer Xenografts

Andiliy Lai, Mehmet Kahraman, Steven P. Govek et al. · Journal of Medicinal Chemistry · 2015 · 247 citations · Full text

, , +13

Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Studies of Intramolecular Heck Reactions of (<i>Z</i>)-α,β-Unsaturated Anilides and Mechanistic Investigations of Asymmetric Heck Reactions Proceeding via Neutral Intermediates

Atsuyuki Ashimori, Benoit Bachand, Michael A. Calter et al. · Journal of the American Chemical Society · 1998 · 185 citations

, , +14

The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer

James D. Joseph, Beatrice Darimont, Wei Zhou et al. · eLife · 2016 · 119 citations · Full text

, , +15

Total Synthesis of Asperazine

Steven P. Govek, Larry E. Overman · Journal of the American Chemical Society · 2001 · 85 citations

, , +7

Maximizing ER-α Degradation Maximizes Activity in a Tamoxifen-Resistant Breast Cancer Model: Identification of GDC-0927

Mehmet Kahraman, Steven P. Govek, Johnny Nagasawa et al. · ACS Medicinal Chemistry Letters · 2018 · 76 citations · Full text

, , +16

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