Andrew J. MacRae

A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex

Rakesh Chatrikhi, Callen F. Feeney, Mary J. Pulvino et al. · Cell chemical biology · 2021 · 37 citations · Full text

Transcriptional Regulation, Early-stage U2af2-rna Complex, Natural Sciences +10

Enantioselective Synthesis of Thailanstatin A Methyl Ester and Evaluation of <i>in Vitro</i> Splicing Inhibition

Arun K. Ghosh, Anne M. Veitschegger, Shenyou Nie et al. · The Journal of Organic Chemistry · 2018 · 29 citations · Full text

Enantioselective Synthesis of Spliceostatin G and Evaluation of Bioactivity of Spliceostatin G and Its Methyl Ester

Arun K. Ghosh, Guddeti Chandrashekar Reddy, Andrew J. MacRae et al. · Organic Letters · 2017 · 20 citations

Medicinal Chemistry, Biosynthesis, Bioorganic Chemistry +11

Prp8 positioning of U5 snRNA is linked to 5′ splice site recognition

Andrew J. MacRae, Megan Mayerle, Eva Hrabeta‐Robinson et al. · RNA · 2018 · 17 citations · Full text