Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

Patricia R. Taylor, Sanhita Roy, Sixto M. Leal, +5

Nature Immunology

InflammationCytokineMicrobial PathogensImmune Cell DevelopmentImmunodeficiencies +11

Tyrosine phosphatase SHP-2 mediates C-type lectin receptor–induced activation of the kinase Syk and anti-fungal TH17 responses

Zihou Deng, Shixin Ma, Hao Zhou, +20

Nature Immunology

Signal TransductionMolecular PhysiologyKinase SykSignaling PathwayAnti-fungal Th17 Responses +8

<i>Aspergillus</i> and <i>Fusarium</i> Corneal Infections Are Regulated by Th17 Cells and IL-17–Producing Neutrophils

Patricia R. Taylor, Sixto M. Leal, Yan Sun, +1

The Journal of Immunology

ExoS and ExoT ADP Ribosyltransferase Activities Mediate <i>Pseudomonas aeruginosa</i> Keratitis by Promoting Neutrophil Apoptosis and Bacterial Survival

Yan Sun, Mausita Karmakar, Patricia R. Taylor, +2

The Journal of Immunology

Microbial PathogensBacterial SurvivalBacteriologyPathologyOcular Surface Physiology +15

Neutrophil elastase contributes to the pathological vascular permeability characteristic of diabetic retinopathy

Haitao Liu, Emma M. Lessieur, Aicha Saadane, +3

Diabetologia

Diabetic RetinopathyOcular DiseaseOphthalmologyDiabetesEndothelial Dysfunction +7

Diabetes-mediated IL-17A enhances retinal inflammation, oxidative stress, and vascular permeability

Sigrún Sigurðardóttir, Thomas E. Zapadka, Sarah I. Lindstrom, +5

Cellular Immunology

InflammationVascular PermeabilityDiabetic RetinopathyCytokineAutoimmune Disease +9

Interleukin-17 Pathophysiology and Therapeutic Intervention in Cystic Fibrosis Lung Infection and Inflammation

Daniel P. Hsu, Patricia R. Taylor, Dave Fletcher, +7

Infection and Immunity

InflammationCytokineInflammatory Lung DiseaseLung InflammationInterleukin-17 Pathophysiology +12

JAK/STAT regulation of <i>Aspergillus fumigatus</i> corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity

Patricia R. Taylor, Sanhita Roy, Evan Meszaros, +4

Journal of Leukocyte Biology

Microbial PathogensFungal Cell BiologyImmunologyImmune RegulationClinical Mycology +20

Diabetes induces IL-17A-Act1-FADD-dependent retinal endothelial cell death and capillary degeneration

Sarah I. Lindstrom, Sigrún Sigurðardóttir, Thomas E. Zapadka, +8

Journal of Diabetes and its Complications

InflammationDiabetic RetinopathyOcular DiseaseAutoimmune DiseaseOphthalmology +12

<i>Aspergillus fumigatus</i> corneal infection is regulated by chitin synthases and by neutrophil–derived acidic mammalian chitinase

Steven de Jesus Carrion, Serena Abbondante, Heather Clark, +10

European Journal of Immunology