Ashwanth C. Francis

Structural and mechanistic bases for a potent HIV-1 capsid inhibitor

S.M. Bester, Guochao Wei, Haiyan Zhao et al. · Science · 2020 · 222 citations · Full text

Molecular Biology, Mechanistic Bases, Antiviral Drug +21

Single HIV-1 Imaging Reveals Progression of Infection through CA-Dependent Steps of Docking at the Nuclear Pore, Uncoating, and Nuclear Transport

Ashwanth C. Francis, Gregory B. Melikyan · Cell Host & Microbe · 2018 · 184 citations · Full text

Virus Structure, Viral Replication, Engineering +14

HIV-1 replication complexes accumulate in nuclear speckles and integrate into speckle-associated genomic domains

Ashwanth C. Francis, Mariana Marin, Parmit K. Singh et al. · Nature Communications · 2020 · 167 citations · Full text

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells

Ashwanth C. Francis, Mariana Marin, Jiong Shi et al. · PLoS Pathogens · 2016 · 124 citations · Full text

Viral Replication, Engineering, Microscopy +21

Siglec-1 initiates formation of the virus-containing compartment and enhances macrophage-to-T cell transmission of HIV-1

J. Hammonds, Neal Beeman, Lingmei Ding et al. · PLoS Pathogens · 2017 · 99 citations · Full text

Viral Replication, Immunology, Viral Pathogenesis +18