The Parvalbumin Hypothesis of Autism Spectrum Disorder

Federica Filice, Lucia Janickova, Thomas Henzi, +2

Frontiers in Cellular Neuroscience

Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome

Theodora Panagaki, Laura Lozano‐Montes, Lucia Janickova, +7

Redox Biology

ER calcium depletion as a key driver for impaired ER-to-mitochondria calcium transfer and mitochondrial dysfunction in Wolfram syndrome

Mailis Liiv, Annika Vaarmann, Dzhamilja Safiulina, +19

Nature Communications

Absence of parvalbumin increases mitochondria volume and branching of dendrites in inhibitory Pvalb neurons in vivo: a point of convergence of autism spectrum disorder (ASD) risk gene phenotypes

Lucia Janickova, Karin Farah Rechberger, Lucas Wey, +1

Molecular Autism

Regulation of mammalian cellular metabolism by endogenous cyanide production

Karim Zuhra, Maria Petrosino, Lucia Janickova, +25

Nature Metabolism

Neurobehavioral dysfunction in a mouse model of Down syndrome: upregulation of cystathionine β-synthase, H2S overproduction, altered protein persulfidation, synaptic dysfunction, endoplasmic reticulum stress, and autophagy

Theodora Panagaki, Lucia Janickova, Dunja Petrovic, +9

GeroScience

Parvalbumin-Deficiency Accelerates the Age-Dependent ROS Production in Pvalb Neurons in vivo: Link to Neurodevelopmental Disorders

Lucia Janickova, Beat Schwaller

Frontiers in Cellular Neuroscience