Parvathy Manoj

Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade

Joy A. Pai, Matthew D. Hellmann, Jennifer L. Sauter et al. · Cancer Cell · 2023 · 139 citations · Full text

Life Sciences, Cancer Biology, Immunology +17

WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

Hirokazu Taniguchi, Rebecca Caeser, Shweta S. Chavan et al. · Cell Reports · 2022 · 131 citations · Full text

Life Sciences, Immunology, Oncology +17

Targeting Lysine-Specific Demethylase 1 Rescues Major Histocompatibility Complex Class I Antigen Presentation and Overcomes Programmed Death-Ligand 1 Blockade Resistance in SCLC

Evelyn M. Nguyen, Hirokazu Taniguchi, Joseph M. Chan et al. · Journal of Thoracic Oncology · 2022 · 131 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer

Andrew Chow, Fathema Uddin, Michael Liu et al. · Immunity · 2022 · 126 citations · Full text

Life Sciences, Immunology, Oncology +17

Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation

Àlvaro Quintanal-Villalonga, Hirokazu Taniguchi, Yingqian A. Zhan et al. · Journal of Hematology & Oncology · 2021 · 93 citations · Full text

Medicine, Cancer Biology, Oncology +17