Leighanne A. Brammer Basta

Loss of a Functionally and Structurally Distinct ld-Transpeptidase, LdtMt5, Compromises Cell Wall Integrity in Mycobacterium tuberculosis

Leighanne A. Brammer Basta, Anita Ghosh, Ying Pan et al. · Journal of Biological Chemistry · 2015 · 57 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem

Mario A. Bianchet, Ying Pan, Leighanne A. Brammer Basta et al. · BMC Biochemistry · 2017 · 52 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Defining critical residues for substrate binding to 1‐deoxy‐<scp>d</scp>‐xylulose 5‐phosphate synthase – active site substitutions stabilize the predecarboxylation intermediate C2α‐lactylthiamin diphosphate

Leighanne A. Brammer Basta, Hetalben Patel, Lazaros T. Kakalis et al. · FEBS Journal · 2014 · 43 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Manipulating the 3D organization of the largest synthetic yeast chromosome

Weimin Zhang, Luciana Lazar‐Stefanita, Hitoyoshi Yamashita et al. · Molecular Cell · 2023 · 35 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Atypically Modified Carbapenem Antibiotics Display Improved Antimycobacterial Activity in the Absence of β-Lactamase Inhibitors

Rashmi Gupta, Noora Mohammed S.A Al-Kharji, Maha A. Alqurafi et al. · ACS Infectious Diseases · 2021 · 25 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17