Guanghui Yang

Sampling the conformational space of the catalytic subunit of human γ-secretase

Xiao‐chen Bai, Eeson Rajendra, Guanghui Yang et al. · eLife · 2015 · 596 citations · Full text

Protein Assembly, γ-Secretase Structure, Molecular Biology +17

An atomic structure of human γ-secretase

Xiao‐chen Bai, Chuangye Yan, Guanghui Yang et al. · Nature · 2015 · 514 citations · Full text

Protein Chemistry, Protein Secretion, Biochemistry +6

Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of Aβ42 and Aβ40 peptides by γ-secretase

Linfeng Sun, Rui Zhou, Guanghui Yang et al. · Proceedings of the National Academy of Sciences · 2016 · 374 citations · Full text

Molecular Biology, Amyloid Precursor Protein, Synaptic Signaling +20

Three-dimensional structure of human γ-secretase

Peilong Lu, Xiao‐chen Bai, Dan Ma et al. · Nature · 2014 · 351 citations · Full text

Protein Secretion, Biochemistry, Natural Sciences +5

Recognition of the amyloid precursor protein by human γ-secretase

Rui Zhou, Guanghui Yang, Xuefei Guo et al. · Science · 2019 · 298 citations