Paul Tolstoshev

T Lymphocyte-Directed Gene Therapy for ADA ⁻ SCID: Initial Trial Results After 4 Years

R. Michael Blaese, Kenneth W. Culver, A. Dusty Miller et al. · Science · 1995 · 1.5K citations

Cloning and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis.

Richard P. Harvey, Eric Degryse, Lenita M. Stefani et al. · Proceedings of the National Academy of Sciences · 1986 · 202 citations · Full text

Genetics, Bacteriology, Molecular Biology +18

Isolation of a human anti-haemophilic factor IX cDNA clone using a unique 52-base synthetic oligonucleotide probe deduced from the amino acid sequence of bovine factor IX

Michael Jaye, Henri de la Salle, Fabienne Schamber et al. · Nucleic Acids Research · 1983 · 161 citations · Full text

Regional localization on the human X chromosome and polymorphism of the coagulation factor IX gene (hemophilia B locus).

Giovanna Camerino, K.-H. Grzeschik, Michael Jaye et al. · Proceedings of the National Academy of Sciences · 1984 · 160 citations · Full text

Regional Localization, Hemophilia B Locus, Factor Ix +15

High-level production of biologically active human alpha 1-antitrypsin in Escherichia coli.

Michael Courtney, Anne Buchwalder, L.H. Tessier et al. · Proceedings of the National Academy of Sciences · 1984 · 140 citations · Full text

Biosynthesis, High-level Production, Protein Function +15