Matthias Kettwig

A multicenter, randomized, placebo-controlled, double-blind phase 3 trial with open-arm comparison indicates safety and efficacy of nephroprotective therapy with ramipril in children with Alport’s syndrome

Burkhard Tönshoff, Lutz T. Weber, Lars Pape et al. · Kidney International · 2020 · 153 citations · Full text

Pharmacy, Pediatrics, Pharmacotherapy +11

Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2

Thomas Ostendorf, Thomas Zillinger, Katarzyna Andryka et al. · Immunity · 2020 · 149 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Mesenchymal Hamartoma of the Liver and DICER1 Syndrome

María Apellániz-Ruiz, Matthias Kettwig, Dylan Pelletier et al. · New England Journal of Medicine · 2019 · 61 citations · Full text

Medicine, Molecular Genetics, Pathology +15

Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

Matthias Kettwig, Katharina Ternka, Kristin Wendland et al. · Nature Communications · 2021 · 38 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Initial insight into the function of the lysosomal 66.3 kDa protein from mouse by means of X-ray crystallography

K. Lakomek, Achim Dickmanns, Matthias Kettwig et al. · BMC Structural Biology · 2009 · 23 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17