Bill Hakim

Charge-based drug delivery to cartilage: Hydrophobic and not electrostatic interactions are the dominant cause of competitive binding of cationic carriers in synovial fluid

Armin Vedadghavami, Tengfei He, Chenzhen Zhang et al. · Acta Biomaterialia · 2022 · 46 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +10

Cationic-motif-modified exosomes for mRNA delivery to retinal photoreceptors

Héctor A. Millán Cotto, Tanvi Vinod Pathrikar, Bill Hakim et al. · Journal of Materials Chemistry B · 2024 · 28 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +15

Cationic peptide carriers enable long-term delivery of insulin-like growth factor-1 to suppress osteoarthritis-induced matrix degradation

Armin Vedadghavami, Bill Hakim, Tengfei He et al. · Arthritis Research & Therapy · 2022 · 22 citations · Full text

Pharmacy, Orthopedic Surgery, Pharmaceutics +17

Cartilage-targeting exosomes for delivery of receptor antagonist of interleukin-1 in osteoarthritis treatment

Tanvi Vinod Pathrikar, Helna Mary Baby, Bill Hakim et al. · Osteoarthritis and Cartilage · 2025 · 18 citations · Full text

Pharmacy, Immunology, Pharmaceutics +16

Cartilage targeting cationic peptide carriers display deep cartilage penetration and retention in a rabbit model of post-traumatic osteoarthritis

Timothy L. Boyer, Olivia Chao, Bill Hakim et al. · Osteoarthritis and Cartilage · 2025 · 12 citations · Full text

Pharmacy, Orthopaedic Surgery, Pharmaceutics +17