Le Qu

TFEB regulates cellular labile iron and prevents ferroptosis in a TfR1-dependent manner

Leilei Chen, Yue Ma, Xizhen Ma et al. · Free Radical Biology and Medicine · 2023 · 93 citations

Life Sciences, Cell Biology, Molecular Biology +11

Cell senescence induced by toxic interaction between α-synuclein and iron precedes nigral dopaminergic neuron loss in a mouse model of Parkinson’s disease

Qingqing Shen, Xian-hui Jv, Xizhen Ma et al. · Acta Pharmacologica Sinica · 2023 · 81 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Rosmarinic acid protects against MPTP-induced toxicity and inhibits iron-induced α-synuclein aggregation

Le Qu, Huamin Xu, Wenting Jia et al. · Neuropharmacology · 2018 · 46 citations

Life Sciences, Biochemistry, Neuroscience +11

Iron-induced oxidative stress contributes to α-synuclein phosphorylation and up-regulation via polo-like kinase 2 and casein kinase 2

Ranran Wang, Youcui Wang, Le Qu et al. · Neurochemistry International · 2019 · 40 citations

Life Sciences, Biochemistry, Neuroscience +8

Gut microbiota-induced CXCL1 elevation triggers early neuroinflammation in the substantia nigra of Parkinsonian mice

Xizhen Ma, Leilei Chen, Le Qu et al. · Acta Pharmacologica Sinica · 2023 · 33 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14