Eric Stefan

Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

Steven M. Corsello, Rohith T. Nagari, Ryan D. Spangler et al. · Nature Cancer · 2020 · 831 citations · Full text

Tumor Biology, Systematic Viability Profiling, Medicine +12

Discovery and SAR of 5-(3-Chlorophenylamino)benzo[<i>c</i>][2,6]naphthyridine-8-carboxylic Acid (CX-4945), the First Clinical Stage Inhibitor of Protein Kinase CK2 for the Treatment of Cancer

Fabrice Pierre, Peter Chua, Sean O’Brien et al. · Journal of Medicinal Chemistry · 2010 · 295 citations · Full text

Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer

Fabrice Pierre, Peter Chua, Sean O’Brien et al. · Molecular and Cellular Biochemistry · 2011 · 151 citations

Medicine, Cancer Growth, Immune Checkpoint Inhibitor +8

Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription

Nicholas B. Struntz, Andrew Chen, Anja Deutzmann et al. · Cell chemical biology · 2019 · 132 citations · Full text

Transcriptional Regulation, Molecular Regulation, Natural Sciences +10

7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: A novel class of Pim kinase inhibitors with potent cell antiproliferative activity

Fabrice Pierre, Eric Stefan, Anne-Sophie Nédellec et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 52 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11