Different Dose-Dependent Mechanisms Are Involved in Early Cyclosporine A-Induced Cholestatic Effects in HepaRG Cells

Ahmad Sharanek, Pamela Bachour-El Azzi, Houssein Al‐Attrache, +5

Toxicological Sciences

In vitro kinetics of amiodarone and its major metabolite in two human liver cell models after acute and repeated treatments

Giuliana Pomponio, Camille C. Savary, C. Parmentier, +6

Toxicology in Vitro

Major MetaboliteHepatologyBiochemistryPharmacological StudyMedicine +10

Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems

Patricia Bellwon, Germaine L. Truisi, Frédéric Y. Bois, +13

Toxicology in Vitro

BiochemistryLiver PhysiologyCell CultureCyclosporine AMetabolism +3

3D multi-cell-type liver organoids: A new model of non-alcoholic fatty liver disease for drug safety assessments

Julie Bronsard, Camille C. Savary, Julie Massart, +8

Toxicology in Vitro

Understanding the biokinetics of ibuprofen after single and repeated treatments in rat and human in vitro liver cell systems

Germaine L. Truisi, Emma Di Consiglio, C. Parmentier, +10

Toxicology Letters

HepatologyPharmacological StudyRepeated TreatmentsMedicineLiver Physiology +9

Impact of Inflammation on Chlorpromazine-Induced Cytotoxicity and Cholestatic Features in HepaRG Cells

Pamela Bachour-El Azzi, Ahmad Sharanek, Ziad Abdel‐Razzak, +8

Drug Metabolism and Disposition

Biokinetics of chlorpromazine in primary rat and human hepatocytes and human HepaRG cells after repeated exposure

Jessica J.W. Broeders, C. Parmentier, Germaine L. Truisi, +10

Toxicology in Vitro

Primary RatAllergyHepatologyHuman Heparg CellsMedicine +7

Impact of isomalathion on malathion cytotoxicity and genotoxicity in human HepaRG cells

Rozenn Jossé, Ahmad Sharanek, Camille C. Savary, +1

Chemico-Biological Interactions

Malathion CytotoxicityHuman Heparg CellsMedicineImmunologyToxicology +2

Interactions of Endosulfan and Methoxychlor Involving CYP3A4 and CYP2B6 in Human HepaRG Cells

Camille C. Savary, Rozenn Jossé, Arnaud Bruyère, +3

Drug Metabolism and Disposition

Transcriptomic analysis of untreated and drug-treated differentiated HepaRG cells over a 2-week period

Camille C. Savary, Xiaoqi Jiang, Marc Aubry, +4

Toxicology in Vitro