Amy J. Osborne

Statistical Validation of Rare Complement Variants Provides Insights into the Molecular Basis of Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy

Amy J. Osborne, Matteo Breno, Nicolò Ghiringhelli Borsa et al. · The Journal of Immunology · 2018 · 159 citations · Full text

New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3

Elizabeth Rodríguez, Pavithra M. Rallapalli, Amy J. Osborne et al. · Bioscience Reports · 2014 · 73 citations · Full text

Structural Bioinformatics, Genetics, Molecular Biology +18

Natural History and Clinicopathological Associations of TRPC6-Associated Podocytopathy

Benjamin Wooden, Andrew Beenken, Elena Martinelli et al. · Journal of the American Society of Nephrology · 2024 · 12 citations · Full text

Two distinct conformations of factor H regulate discrete complement-binding functions in the fluid phase and at cell surfaces

Amy J. Osborne, Ruodan Nan, Ami Miller et al. · Journal of Biological Chemistry · 2018 · 10 citations · Full text

Protein Function, Fluid Phase, Protein Folding +12