Concepedia

Luke A. Perera

LA

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Publications

7

Citations

520

H-Index

7

Active since

2016

Affiliations

University of Cambridge(Current)

RIKEN Center for Biosystems Dynamics Research

Luke A. Perera is an author at University of Cambridge specializing in medicine, cellular biochemistry, and natural sciences.

ORCID

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Publications per year

2016–2023

7

Publications

7

ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B

Alisa Zyryanova, Kazuhiro Kashiwagi, Cláudia Rato et al. · Molecular Cell · 2020 · 192 citations · Full text

, , +21

FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP

Cláudia Rato, Luke A. Perera, Vladimı́r Saudek et al. · Nature Structural & Molecular Biology · 2016 · 107 citations · Full text

, , +9

Calcium depletion challenges endoplasmic reticulum proteostasis by destabilising BiP-substrate complexes

Cláudia Rato, Yahui Yan, Luke A. Perera et al. · eLife · 2020 · 88 citations · Full text

, , +18

An oligomeric state‐dependent switch in the <scp>ER</scp> enzyme <scp>FICD</scp> regulates <scp>AMP</scp> ylation and de <scp>AMP</scp> ylation of BiP

Luke A. Perera, Cláudia Rato, Yahui Yan et al. · The EMBO Journal · 2019 · 53 citations · Full text

Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD

Luke A. Perera, Nathan R. Zaccai, Sylvain Prévost et al. · Nature Communications · 2021 · 31 citations · Full text

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