Nicholas E. Geacintov

Influence of benzo[a]pyrenediol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.cntdot.C adduct structure and comparison with the (+)-trans-anti[BP]G.cntdot.C enantiomer

Carlos de los Santos, Monique Cosman, Brian E. Hingerty et al. · Biochemistry · 1992 · 139 citations

Life Sciences, Biochemistry, Chemistry +9

Solution Conformation of the (-)-trans-anti-Benzo[c]phenanthrene-dA ([BPh]dA) Adduct opposite dT in a DNA Duplex: Intercalation of the Covalently Attached Benzo[c]phenanthrenyl Ring to the 3'-Side of the Adduct Site and Comparison with the (+)-trans-anti-[BPh]dA opposite dT Stereoisomer

Monique Cosman, Alfred Laryea, Radovan Fiala et al. · Biochemistry · 1995 · 63 citations

Pharmacy, Biochemistry, Chemistry +11

The Major, N2-Gua Adduct of the (+)-anti-Benzo[a]pyrene Diol Epoxide Is Capable of Inducing G.fwdarw.A and G.fwdarw.C, in Addition to G.fwdarw.T, Mutations

Scott A. Jelinsky, Tongming Liu, Nicholas E. Geacintov et al. · Biochemistry · 1995 · 57 citations

Life Sciences, Biochemistry, Molecular Biology +17

Conformational studies of the (+)-trans, (−)-trans, (+)-cis, and (−)-cis adducts of anti-benzo[a]pyrene diolepoxide to N2-dG in duplex oligonucleotides using polyacrylamide gel electrophoresis and low-temperature fluorescence spectroscopy

Myungkoo Suh, Freek Ariese, G. J. Small et al. · Biophysical Chemistry · 1995 · 44 citations

Pharmacy, Biochemistry, Chemistry +17

Direct Synthesis and Characterization of Site-Specific Adenosyl Adducts Derived from the Binding of a 3,4-Dihydroxy-1,2-epoxybenzo[c]phenanthrene Stereoisomer to an 11-mer Oligodeoxyribonucleotide

Alfred Laryea, Monique Cosman, Jyh-Ming Lin et al. · Chemical Research in Toxicology · 1995 · 32 citations

Pharmacy, Biochemistry, Chemistry +9