The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host

Gülşah Gabriel, Bianca Dauber, Thorsten Wolff, +3

Proceedings of the National Academy of Sciences

Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade

Stephan Pleschka, Thorsten Wolff, Christina Ehrhardt, +4

Nature Cell Biology

Raf/mek/erk Signalling CascadePathogenesisViral PathogenesisInfluenza Virus PropagationVirology +3

Influenza A Virus NS1 Protein Activates the PI3K/Akt Pathway To Mediate Antiapoptotic Signaling Responses

Christina Ehrhardt, Thorsten Wolff, Stephan Pleschka, +5

Journal of Virology

NF-κB-dependent Induction of Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) and Fas/FasL Is Crucial for Efficient Influenza Virus Propagation

Walter J. Wurzer, Christina Ehrhardt, Stephan Pleschka, +5

Journal of Biological Chemistry

Innate Immune SystemViral PathogenesisImmunologyPathologyCell Death +16

Bivalent role of the phosphatidylinositol-3-kinase (PI3K) during influenza virus infection and host cell defence

Christina Ehrhardt, Henju Marjuki, Thorsten Wolff, +4

Cellular Microbiology

Viral PathogenesisImmunologyViral Structural ProteinInfluenza VaccinesCell Signaling +15

NF-κB Pathway as a Potential Target for Treatment of Critical Stage COVID-19 Patients

Ralf Kircheis, Emanuel Haasbach, Daniel Lueftenegger, +3

Frontiers in Immunology

Inflammatory Lung DiseaseLung InflammationImmunologyImmune RegulationInnate Immunity +22

Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-?B-inhibiting activity

Igor Mazur, Walter J. Wurzer, Christina Ehrhardt, +6

Cellular Microbiology

Medicinal ChemistryAcetylsalicylic AcidMedicineB-inhibiting ActivityImmunology +11

A critical role for neutralizing-antibody-producing B cells, CD4⁺T cells, and interferons in persistent and acute infections of mice with lymphocytic choriomeningitis virus: Implications for adoptive immunotherapy of virus carriers

Oliver Planz, Stephan Ehl, Esther Furrer, +4

Proceedings of the National Academy of Sciences

The Influenza A Virus NS1 Protein Inhibits Activation of Jun N-Terminal Kinase and AP-1 Transcription Factors

Stephan Ludwig, Xiuyan Wang, Christina Ehrhardt, +7

Journal of Virology

Host ResponseSystems BiologyImmunologyViral PathogenesisJun N-terminal Kinase +11

A polyphenol rich plant extract, CYSTUS052, exerts anti influenza virus activity in cell culture without toxic side effects or the tendency to induce viral resistance

Christina Ehrhardt, Eike-Roman Hrincius, Virginia Dipl. Biol. Korte, +7

Antiviral Research

MedicineVirologyCell CultureInfluenza VaccineViral Resistance +5