Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis

Congqing Wu, Wei Lu, Yan Zhang, +17

Immunity

InflammationNecroptosisApoptosisAutophagyImmunology +9

Platelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway

Binggang Xiang, Guoying Zhang, Ling Guo, +6

Nature Communications

InflammationThrombosisThrombopoiesisBlood PlateletHematology +12

Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis

Madhu M. Ouseph, Yunjie Huang, Meenakshi Banerjee, +13

Blood

Arf6 controls platelet spreading and clot retraction via integrin αIIbβ3 trafficking

Yunjie Huang, Smita Joshi, Binggang Xiang, +5

Blood

Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation

Guoying Zhang, Binggang Xiang, Anping Dong, +5

Blood

Distinct Roles for Rap1b Protein in Platelet Secretion and Integrin αIIbβ3 Outside-in Signaling

Guoying Zhang, Binggang Xiang, Shaojing Ye, +7

Journal of Biological Chemistry

Protein SecretionImmunologyCytoskeletonPlatelet AggregationCellular Physiology +19

The Src Family Kinases and Protein Kinase C Synergize to Mediate Gq-dependent Platelet Activation

Binggang Xiang, Guoying Zhang, Lucia Stefanini, +4

Journal of Biological Chemistry

ThrombopoiesisThrombosisSignal TransductionMolecular PhysiologyBlood Platelet +13

Characterization of a Novel Integrin Binding Protein, VPS33B, Which Is Important for Platelet Activation and In Vivo Thrombosis and Hemostasis

Binggang Xiang, Guoying Zhang, Shaojing Ye, +8

Circulation

A Gi‐independent mechanism mediating Akt phosphorylation in platelets

Binggang Xiang, G. Zhang, J. Liu, +4

Journal of Thrombosis and Haemostasis

Molecular PhysiologySignal TransductionBlood PlateletCell SignalingGi‐independent Mechanism +7

The P2Y12 Antagonists, 2MeSAMP and Cangrelor, Inhibit Platelet Activation through P2Y12/Gi-Dependent Mechanism

Binggang Xiang, Guoying Zhang, Hongmei Ren, +5

PLoS ONE