Safety, tolerability, pharmacokinetics, and immunogenicity of a human monoclonal antibody targeting the G glycoprotein of henipaviruses in healthy adults: a first-in-human, randomised, controlled, phase 1 study

E. Geoffrey Playford, Trent P. Munro, Stephen M. Mahler, +21

The Lancet Infectious Diseases

VaccinationVeterinary VaccineHuman Monoclonal AntibodyImmunologyVirology +3

High-throughput ClonePix FL analysis of mAb-expressing clones using the UCOE expression system

Jeff Jia Cheng Hou, Benjamin Hughes, Matthew Smede, +5

New Biotechnology

EngineeringMolecular Biological MethodUcoe Expression SystemMedicineBioanalysis +11

Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2

Daniel Watterson, Danushka K. Wijesundara, Naphak Modhiran, +47

Clinical & Translational Immunology

Enhanced CHO Cell-Based Transient Gene Expression with the Epi-CHO Expression System

Joe Codamo, Trent P. Munro, Benjamin Hughes, +2

Molecular Biotechnology

Signal TransductionSignaling PathwayProtein ExpressionCell RegulationGene Expression +8

New frontiers in cell line development: challenges for biosimilars

Jeff Jia Cheng Hou, Joe Codamo, Warren Pilbrough, +3

Journal of Chemical Technology & Biotechnology

Gene AmplificationEngineeringCell CultureGenetic TechnologyBioengineering +17

Efficient mAb production in CHO cells incorporating PEI‐mediated transfection, mild hypothermia and the co‐expression of XBP‐1

Joe Codamo, Jeff Jia Cheng Hou, Benjamin Hughes, +2

Journal of Chemical Technology & Biotechnology

Immune RegulationImmunologyBlood CellImmunologic MechanismGene Delivery +18

Establishment of Higher Passage PER.C6 Cells for Adenovirus Manufacture

Marina Berdichevsky, M.-P. Gentile, Benjamin Hughes, +5

Biotechnology Progress

Viral ReplicationVirologyCell CulturePer.c6 CellsHp Per.c6 +5

Clonal selection of high producing, stably transfected HEK293 cell lines utilizing modified, high‐throughput FACS screening

Michael Song, Kristin Raphaelli, Martina L. Jones, +8

Journal of Chemical Technology & Biotechnology

Hek293 Cell LinesEngineeringMolecular BiologyCell CultureProtein Purification +16

Pilot-Scale Adenovirus Seed Production through Concurrent Virus Release and Concentration by Hollow Fiber Filtration

Shyamsundar Subramanian, Gina M. Altaras, Jennifer Chen, +3

Biotechnology Progress

Virus StructureBiomanufacturingCell LysisEngineeringSynthetic Virology +11

Purification of transferrin from Cohn supernatant I using ion‐exchange chromatography

Karl B. McCann, Benjamin Hughes, John Y P Wu, +2

Biotechnology and Applied Biochemistry