Tom Huxford

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

Scott B. Hansen, Gerlind Sulzenbacher, Tom Huxford et al. · The EMBO Journal · 2005 · 627 citations · Full text

Distinctive Binding Interfaces, Signal Transduction, Biochemistry +11

The Crystal Structure of the IκBα/NF-κB Complex Reveals Mechanisms of NF-κB Inactivation

Tom Huxford, D. Huang, Shiva Malek et al. · Cell · 1998 · 576 citations · Full text

Crystal Structure, Signal Transduction, Cell Regulation +13

IκBβ, but Not IκBα, Functions as a Classical Cytoplasmic Inhibitor of NF-κB Dimers by Masking Both NF-κB Nuclear Localization Sequences in Resting Cells

Shiva Malek, Yi Chen, Tom Huxford et al. · Journal of Biological Chemistry · 2001 · 173 citations · Full text

IκBα Functions through Direct Contacts with the Nuclear Localization Signals and the DNA Binding Sequences of NF-κB

Shiva Malek, Tom Huxford, Gourisankar Ghosh · Journal of Biological Chemistry · 1998 · 152 citations · Full text

X-ray Crystal Structure of an IκBβ·NF-κB p65 Homodimer Complex

Shiva Malek, D. Huang, Tom Huxford et al. · Journal of Biological Chemistry · 2003 · 121 citations · Full text