Matthew I. Radle

A Radically Different Mechanism for <i>S</i> -Adenosylmethionine–Dependent Methyltransferases

Tyler L. Grove, Jack S. Benner, Matthew I. Radle et al. · Science · 2011 · 223 citations

Cfr and RlmN Contain a Single [4Fe-4S] Cluster, which Directs Two Distinct Reactivities for <i>S</i> -Adenosylmethionine: Methyl Transfer by S _N 2 Displacement and Radical Generation

Tyler L. Grove, Matthew I. Radle, Carsten Krebs et al. · Journal of the American Chemical Society · 2011 · 65 citations · Full text

Further Characterization of Cys-Type and Ser-Type Anaerobic Sulfatase Maturating Enzymes Suggests a Commonality in the Mechanism of Catalysis

Tyler L. Grove, Jessica H. Ahlum, Rosie Qin et al. · Biochemistry · 2013 · 62 citations · Full text

Methanogenesis marker protein 10 (Mmp10) from Methanosarcina acetivorans is a radical S-adenosylmethionine methylase that unexpectedly requires cobalamin

Matthew I. Radle, Danielle V. Miller, Tatiana N. Laremore et al. · Journal of Biological Chemistry · 2019 · 48 citations · Full text

Characterization of a Cross-Linked Protein–Nucleic Acid Substrate Radical in the Reaction Catalyzed by RlmN

Alexey Silakov, Tyler L. Grove, Matthew I. Radle et al. · Journal of the American Chemical Society · 2014 · 44 citations · Full text

C2 Methylation, Nucleic Acid Chemistry, Biochemistry +12