Jeff R. Jorgensen

Direct-to-Biology Accelerates PROTAC Synthesis and the Evaluation of Linker Effects on Permeability and Degradation

Charles E. Hendrick, Jeff R. Jorgensen, Charu Chaudhry et al. · ACS Medicinal Chemistry Letters · 2022 · 131 citations · Full text

Engineering, Biomolecular Tool, Linker Structure-activity Relationships +19

ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins

Lu Zhu, Jeff R. Jorgensen, Ming Li et al. · eLife · 2017 · 126 citations · Full text

The Hob proteins are novel and conserved lipid-binding proteins at ER–PM contact sites

Sarah D. Neuman, Jeff R. Jorgensen, Amy T. Cavanagh et al. · Journal of Cell Science · 2021 · 39 citations · Full text

A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling

S. Suzuki, Akihiko Oishi, N. Nikulin et al. · eLife · 2021 · 38 citations · Full text

Protein Function, Natural Sciences, Membrane Scission +12

ESCRT-III and ER–PM contacts maintain lipid homeostasis

Jeff R. Jorgensen, Reika Tei, Jeremy M. Baskin et al. · Molecular Biology of the Cell · 2020 · 31 citations · Full text