Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

Jin Wei, Mia Madel Alfajaro, Peter C. DeWeirdt, +28

Cell

Sars-cov-2 InfectionPathogenesisVirologyGene EditingGenome Editing +6

PD-L1 promotes colorectal cancer stem cell expansion by activating HMGA1-dependent signaling pathways

Wei Fang, Tong Zhang, Shu-Chou Deng, +8

Cancer Letters

OncologyMedicineColorectal CancerHmga1-dependent Signaling PathwaysTumor Suppressor +6

Long noncoding RNA PVT1-214 promotes proliferation and invasion of colorectal cancer by stabilizing Lin28 and interacting with miR-128

Feng He, Zhi Song, Huacui Chen, +10

Oncogene

Tumor BiologyMedicineColorectal CancerCancer GenomicsLong Non-coding Rna +8

Genome-wide CRISPR screen reveals host genes that regulate SARS-CoV-2 infection

Jin Wei, Mia Madel Alfajaro, Ruth E. Hanna, +24

Highlights Host GenesSars-cov-2 InfectionPathogenesisImmunologyViral Pathogenesis +13

Expression of EZH2 is associated with poor outcome in colorectal cancer

Zhuanpeng Chen, Ping Yang, Wanglin Li, +6

Oncology Letters

Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression

Feng He, Huacui Chen, Ping Yang, +8

Oncotarget

Long non‑coding RNA 00152 functions as a competing endogenous RNA to regulate NRP1 expression by sponging with miRNA‑206 in colorectal cancer

Zhuanpeng Chen, Jianchang Wei, Qiang Wang, +7

International Journal of Oncology

EngineeringPathologyRna 00152Crc CellsCancer Biology +20

Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation

Wesley L. Cai, Jocelyn Fang-Yi Chen, Huacui Chen, +16

eLife

Breast Cancer GrowthBreast OncologyCancer BiologyTumor BiologyCell Regulation +18

Gambogic Acid Efficiently Kills Stem-Like Colorectal Cancer Cells by Upregulating ZFP36 Expression

Wei Fang, Tong Zhang, Zhi Yang, +11

Cellular Physiology and Biochemistry

Gambogic acid potentiates the chemosensitivity of colorectal cancer cells to 5-fluorouracil by inhibiting proliferation and inducing apoptosis

Jianchang Wei, Ping Yang, Wanglin Li, +10

Experimental and Therapeutic Medicine

Tumor BiologyChemoprevention StrategyMedicinePharmacologyColorectal Cancer +13