The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms

Yusuke Mimura, S. Church, Rodolfo Ghirlando, +5

Molecular Immunology

GlycoproteomicsSignal TransductionGlycosylationBiochemistryNatural Sciences +8

Role of Oligosaccharide Residues of IgG1-Fc in FcγRIIb Binding

Yusuke Mimura, Peter Sondermann, Rodolfo Ghirlando, +4

Journal of Biological Chemistry

Multiple interactions of IgG with its core oligosaccharide can modulate recognition by complement and human Fc γ receptor I and influence the synthesis of its oligosaccharide chains

John Lund, Nobuhiro Takahashi, John D. Pound, +2

The Journal of Immunology

Human Fc gamma RI and Fc gamma RII interact with distinct but overlapping sites on human IgG

John Lund, Gerhard Winter, Peter Jones, +8

The Journal of Immunology

Aglycosylation of human IgG1 and IgG3 monoclonal antibodies can eliminate recognition by human cells expressing FcγRI and/or FcγRII receptors

M R Walker, John Lund, K. M. Thompson, +1

Biochemical Journal

Immunocytochemical TechniqueImmunodeficienciesImmunologyImmune RegulationImmunodominance +23

A comparative study of the <i>N</i>-linked oligosaccharide structures of human IgG subclass proteins

Roy Jefferis, John Lund, Haruo Mizutani, +4

Biochemical Journal

GlycobiologyMolecular BiologyPolysaccharideAnalytical UltracentrifugationProteomics +14

A protein structural change in aglycosylated IgG3 correlates with loss of huFcγR1 and hufcγR111 binding and/or activation

John Lund, Toshiyuki Tanaka, Takahashi Noriko, +3

Molecular Immunology

Molecular ImmunologyProtein FunctionSignal TransductionGlycosylationMedicine +12

FcαRI (CD89) as a Novel Trigger Molecule for Bispecific Antibody Therapy

Thomas Valerius, Bernhard Stockmeyer, Annemiek B. van Spriel, +8

Blood

Electron transfer reactions in the soluble methane monooxygenase of <i>Methylococcus capsulatus</i> (Bath)

John Lund, Marc P. Woodland, Howard Dalton

European Journal of Biochemistry

Mapping and comparison of the interaction sites on the Fc region of IgG responsible for triggering antibody dependent cellular cytotoxicity (ADCC) through different types of human Fcγ receptor

Gabriella Sármay, John Lund, Zoltán Rozsnyay, +2

Molecular Immunology