Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes

Stephan Brouwer, Timothy C. Barnett, Diane Ly, +16

Nature Communications

Comparison of peripheral blood mononuclear cell isolation techniques and the impact of cryopreservation on human lymphocytes expressing CD39 and CD73

Ross J. Turner, Nicholas J. Geraghty, Jonathan G. Williams, +7

Purinergic Signalling

Cell TherapyMedicineImmunologyHematologyImmunophenotyping +5

Plasmin(ogen) Acquisition by Group A <b><i>Streptococcus</i></b> Protects against C3b-Mediated Neutrophil Killing

Diane Ly, Jude Taylor, James A. Tsatsaronis, +10

Journal of Innate Immunity

The P2X7 receptor antagonist JNJ-47965567 administered thrice weekly from disease onset does not alter progression of amyotrophic lateral sclerosis in SOD1G93A mice

Diane Ly, Anjila Dongol, Peter Cuthbertson, +8

Purinergic Signalling

Amyotrophic Lateral SclerosisMedicineSod1g93a MiceNeuropharmacologyDisease Onset +6

An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics

Albi Celaj, Alice Jiexin Gao, Tammy T.Y. Lau, +43

EngineeringGeneticsMolecular BiologyTranscriptomics TechnologyDisease Mechanisms +25

Increased P2X7 expression in the gastrointestinal tract and skin in a humanised mouse model of graft-versus-host disease

Peter Cuthbertson, Sam Adhikary, Nicholas J. Geraghty, +6

Clinical Science

A Key Role for the Urokinase Plasminogen Activator (uPA) in Invasive Group A Streptococcal Infection

Martina Sanderson‐Smith, Yueling Zhang, Diane Ly, +7

PLoS Pathogens

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background

Jeremy S. Lum, Mikayla Brown, Natalie E. Farrawell, +12

Scientific Reports

P2X7 receptor antagonism in amyotrophic lateral sclerosis

Ronald Sluyter, Rachael Bartlett, Diane Ly, +1

Neural Regeneration Research

Streptococcus pyogenes M1T1 Variants Induce an Inflammatory Neutrophil Phenotype Including Activation of Inflammatory Caspases

Jonathan G. Williams, Diane Ly, Nicholas J. Geraghty, +6

Frontiers in Cellular and Infection Microbiology