Thirumagal Thiyagarajan

Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer

Suriyan Ponnusamy, Christopher C. Coss, Thirumagal Thiyagarajan et al. · Cancer Research · 2017 · 84 citations · Full text

Orally Bioavailable Androgen Receptor Degrader, Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer

Suriyan Ponnusamy, Yali He, Dong‐Jin Hwang et al. · Clinical Cancer Research · 2019 · 73 citations · Full text

Renal Glycosphingolipid Metabolism Is Dysfunctional in Lupus Nephritis

Tamara K. Nowling, Andrew R. Mather, Thirumagal Thiyagarajan et al. · Journal of the American Society of Nephrology · 2014 · 70 citations · Full text

Glomerular Disease, Renal Pathology, Immunology +20

Pharmacologic activation of estrogen receptor α increases mitochondrial function, energy expenditure, and brown adipose tissue

Suriyan Ponnusamy, Quynh T. Tran, Innocence Harvey et al. · The FASEB Journal · 2016 · 66 citations · Full text

Metabolic Remodeling, Caloric Restriction, Insulin Signaling +25

New Generation of Selective Androgen Receptor Degraders: Our Initial Design, Synthesis, and Biological Evaluation of New Compounds with Enzalutamide-Resistant Prostate Cancer Activity

Dong‐Jin Hwang, Yali He, Suriyan Ponnusamy et al. · Journal of Medicinal Chemistry · 2018 · 64 citations · Full text

Combinatorial Chemistry, Androgen Receptor, Medicinal Chemistry +15