Sarah L. Huszar

Mechanism based neurotoxicity of mGlu5 positive allosteric modulators – Development challenges for a promising novel antipsychotic target

Sophie Parmentier‐Batteur, Peter H. Hutson, Karsten Menzel et al. · Neuropharmacology · 2013 · 93 citations

Molecular Pharmacology, Molecular Neuroscience, Development Challenges +11

The novel phosphodiesterase 10A inhibitor THPP-1 has antipsychotic-like effects in rat and improves cognition in rat and rhesus monkey

Sean M. Smith, Jason M. Uslaner, Christopher D. Cox et al. · Neuropharmacology · 2012 · 84 citations · Full text

Inhibitor Thpp-1, Novel Phosphodiesterase 10A, Behavioral Neuroscience +11

The Behavioral and Neurochemical Effects of a Novel d-Amino Acid Oxidase Inhibitor Compound 8 [4 H-Thieno [3,2-b]pyrrole-5-carboxylic Acid] and d-Serine

Sean M. Smith, Jason M. Uslaner, Lihang Yao et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 81 citations

MK-801 produces a deficit in sucrose preference that is reversed by clozapine, d-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: Relevance to negative symptoms associated with schizophrenia?

Joshua D. Vardigan, Sarah L. Huszar, Caitlyn McNaughton et al. · Pharmacology Biochemistry and Behavior · 2010 · 77 citations

Neuropsychology, Psychiatry, Sucrose Preference +13

Genetic and Pharmacological Evaluation of Cathepsin S in a Mouse Model of Asthma

Kathleen Deschamps, Wanda Cromlish, Sean Weicker et al. · American Journal of Respiratory Cell and Molecular Biology · 2010 · 47 citations

Asthma, Inflammatory Lung Disease, Lung Inflammation +16