Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2

Richard J.L.F. Lemmers, Rabi Tawil, Lisa M. Petek, +25

Nature Genetics

Rare DiseasesDevelopmental BiologyMendelian DisorderGenetic DisorderGenetics +8

Multipotent Stromal Cells Are Activated to Reduce Apoptosis in Part by Upregulation and Secretion of Stanniocalcin-1

Gregory J. Block, Shinya Ohkouchi, France W. Fung, +6

Stem Cells

ApoptosisImmunologyMultipotent Stromal CellsCell DeathCell Proliferation +17

Multipotent stromal cells are activated to reduce apoptosis in part by upregulation and secretion of stanniocalcin-1

Gregory J. Block, Shinya Ohkouchi, France W. Fung, +6

Stem Cells

ApoptosisImmunologyMultipotent Stromal CellsCell DeathCell Proliferation +16

Mesenchymal Stromal Cells Protect Cancer Cells From ROS-induced Apoptosis and Enhance the Warburg Effect by Secreting STC1

Shinya Ohkouchi, Gregory J. Block, Ahmed Katsha, +6

Molecular Therapy

Cell DeathWarburg EffectCancer BiologyTumor BiologyOxidative Stress +14

Wnt/β-catenin signaling suppresses DUX4 expression and prevents apoptosis of FSHD muscle cells

Gregory J. Block, Divya Narayanan, Amanda M. Amell, +6

Human Molecular Genetics

ApoptosisGenomic MechanismCell DeathDisease Gene IdentificationChromatin Relaxation +25

Mechanotransduction of Extracellular Signal-Regulated Kinases 1 and 2 Mitogen-Activated Protein Kinase Activity in Smooth Muscle Is Dependent on the Extracellular Matrix and Regulated by Matrix Metalloproteinases

Karen Aitken, Gregory J. Block, Armando J. Lorenzo, +7

American Journal Of Pathology

MechanobiologyMuscle FunctionSignal TransductionEngineeringSkeletal Muscle +12

One-step isolation of plasma membrane proteins using magnetic beads with immobilized concanavalin A

Yu Chen Lee, Gregory J. Block, Huiwen Chen, +16

Protein Expression and Purification

Membrane FusionBiochemistryNatural SciencesMembrane TransportOne-step Isolation +8

Transcriptional Regulation Is Affected by Subnuclear Targeting of Reporter Plasmids to PML Nuclear Bodies

Gregory J. Block, Christopher H. Eskiw, Graham Dellaire, +1

Molecular and Cellular Biology

Viral ReplicationMolecular BiologyPml NbsTranscriptional RegulationPml Nuclear Bodies +14

Arsenic mediated disruption of promyelocytic leukemia protein nuclear bodies induces ganciclovir susceptibility in Epstein–Barr positive epithelial cells

Mark D Sides, Gregory J. Block, Bin Shan, +4

Virology

Tumor BiologyMedicineImmunologyCell DeathCancer Cell Biology +5

Asymmetric Bidirectional Transcription from the FSHD-Causing D4Z4 Array Modulates DUX4 Production

Gregory J. Block, Lisa M. Petek, Divya Narayanan, +8

PLoS ONE

ChromatinTranscriptional RegulationDevelopmental BiologyFunctional GenomicsProgressive Myopathy +13