John E. DeLorbe

Enantioselective Total Synthesis of (+)-Gliocladine C: Convergent Construction of Cyclotryptamine-Fused Polyoxopiperazines and a General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors

John E. DeLorbe, Salman Jabri, Steven M. Mennen et al. · Journal of the American Chemical Society · 2011 · 166 citations · Full text

Biochemistry, Trioxopiperazine Precursors, Natural Sciences +14

Thermodynamic and Structural Effects of Conformational Constraints in Protein−Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization

John E. DeLorbe, John H. Clements, Martin G. Teresk et al. · Journal of the American Chemical Society · 2009 · 136 citations

Thermodynamic and Structural Effects of Macrocyclic Constraints in Protein−Ligand Interactions

John E. DeLorbe, John H. Clements, Benjamin B. Whiddon et al. · ACS Medicinal Chemistry Letters · 2010 · 92 citations · Full text

General Approach for Preparing Epidithiodioxopiperazines from Trioxopiperazine Precursors: Enantioselective Total Syntheses of (+)- and (−)-Gliocladine C, (+)-Leptosin D, (+)-T988C, (+)-Bionectin A, and (+)-Gliocladin A

John E. DeLorbe, David Horne, Richard Jove et al. · Journal of the American Chemical Society · 2013 · 89 citations · Full text

Ligand Preorganization May Be Accompanied by Entropic Penalties in Protein–Ligand Interactions

Aaron P. Benfield, Martin G. Teresk, Hilary R. Plake et al. · Angewandte Chemie International Edition · 2006 · 82 citations · Full text

Protein Chemistry, Drug Target, Protein–ligand Interactions +15