Constitutively Activated ALK2 and Increased SMAD1/5 Cooperatively Induce Bone Morphogenetic Protein Signaling in Fibrodysplasia Ossificans Progressiva

Toru Fukuda, Masakazu Kohda, Kazuhiro Kanomata, +34

Journal of Biological Chemistry

Dual Roles of Smad Proteins in the Conversion from Myoblasts to Osteoblastic Cells by Bone Morphogenetic Proteins

Junya Nojima, Kazuhiro Kanomata, Yumi Takada, +13

Journal of Biological Chemistry

MechanobiologyTissue EngineeringSclerostinDevelopmental BiologyEngineering +9

A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor

Toru Fukuda, Kazuhiro Kanomata, Junya Nojima, +19

Biochemical and Biophysical Research Communications

FibrosisSignal TransductionBone Morphogenic ProteinFibrodysplasia OssificansPathology +8

Platelet-rich plasma stimulates osteoblastic differentiation in the presence of BMPs

Akihiro Tomoyasu, Kanji Higashio, Kazuhiro Kanomata, +8

Biochemical and Biophysical Research Communications

Regenerative MedicineThrombopoiesisBone Morphogenic ProteinBlood PlateletHematology +7

Nicotine induces cell proliferation in association with cyclin D1 up-regulation and inhibits cell differentiation in association with p53 regulation in a murine pre-osteoblastic cell line

Tsuyoshi Sato, Takahiro Abe, Norimichi Nakamoto, +7

Biochemical and Biophysical Research Communications

Nicotine InducesMedicineNicotineP53 RegulationOsteoporosis +4

Protein phosphatase magnesium-dependent 1A–mediated inhibition of BMP signaling is independent of Smad dephosphorylation

Shoichiro Kokabu, Junya Nojima, Kazuhiro Kanomata, +4

Journal of Bone and Mineral Research

Suppression of BMP-Smad Signaling Axis-Induced Osteoblastic Differentiation by Small C-terminal Domain Phosphatase 1, a Smad Phosphatase

Shoichiro Kokabu, Satoshi Ohte, Hiroki Sasanuma, +9

Molecular Endocrinology

SclerostinDevelopmental BiologySignal TransductionMolecular PhysiologyBone Morphogenic Protein +9

DRAGON, a GPI‐anchored membrane protein, inhibits BMP signaling in C2C12 myoblasts

Kazuhiro Kanomata, Shoichiro Kokabu, Junya Nojima, +2

Genes to Cells

Molecular RegulationGpi‐anchored Membrane ProteinBmp Co-receptorsMolecular BiologyCellular Physiology +15

Expression of TLE3 by bone marrow stromal cells is regulated by canonical Wnt signaling

Shoichiro Kokabu, Tsuyoshi Sato, Satoshi Ohte, +10

FEBS Letters

Low-grade cribriform cystadenocarcinoma of the palatal gland: A case report

Shoichiro Kokabu, Junya Nojima, Hidekazu Kayano, +1

Oncology Letters

Low-grade Cribriform CystadenocarcinomaTumoral PathologySurgical PathologyEar MoldingHistopathology +8