Jordan D. Carelli

Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

Kevin D. Freeman‐Cook, Robert L. Hoffman, Nichol Miller et al. · Cancer Cell · 2021 · 186 citations

Life Sciences, Cancer Biology, Oncology +14

Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer

Kevin D. Freeman‐Cook, Robert L. Hoffman, Douglas C. Behenna et al. · Journal of Medicinal Chemistry · 2021 · 117 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Reversible lysine-targeted probes reveal residence time-based kinase selectivity

Tangpo Yang, Adolfo Cuesta, Xiaobo Wan et al. · Nature Chemical Biology · 2022 · 103 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes

Keely Oltion, Jordan D. Carelli, Tangpo Yang et al. · Cell · 2023 · 80 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex

Jordan D. Carelli, Steven G. Sethofer, Geoffrey A. Smith et al. · eLife · 2015 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +14