Niklas Bruse

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19

Joana P. Bernardes, Neha Mishra, Florian Tran et al. · Immunity · 2020 · 407 citations · Full text

Life Sciences, Cell Biology, Hematology +16

Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients

Anna C. Aschenbrenner, Maria Mouktaroudi, Benjamin Krämer et al. · Genome Medicine · 2021 · 278 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes

Guus P. Leijte, Thomas Rimmelé, Matthijs Kox et al. · Critical Care · 2020 · 156 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +15

GimmeMotifs: an analysis framework for transcription factor motif analysis

Niklas Bruse, Simon J. van Heeringen · bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 89 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +15

Dexamethasone and tocilizumab treatment considerably reduces the value of C-reactive protein and procalcitonin to detect secondary bacterial infections in COVID-19 patients

Emma J. Kooistra, Miranda van Berkel, N. Kempen et al. · Critical Care · 2021 · 85 citations · Full text

Veterinary Medicine, Clinical Sciences, Infectious Diseases +15