J. M. Gubbens‐Stibbe

Rectal bioavailability of lidocaine in man: Partial avoidance of “first‐pass” metabolism

Albertus G. de Boer, D. D. Breimer, H. Mattie et al. · Clinical Pharmacology & Therapeutics · 1979 · 93 citations

Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of the Electroencephalogram Effects of GABAA Receptor Modulators: In Vitro-in Vivo Correlations

Sandra A. G. Visser, Francisca L.C. Wolters, J. M. Gubbens‐Stibbe et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 84 citations

lontophoretic Delivery of Apomorphine II: An In Vivo Study in Patients with Parkinson's Disease

Ronald van der Geest, Teus van Laar, J. M. Gubbens‐Stibbe et al. · Pharmaceutical Research · 1997 · 61 citations

The Comparative Pharmacodynamics of Remifentanil and Its Metabolite, GR90291, in a Rat Electroencephalographic Model 

Eugène Cox, M.W.E. Langemeijer, J. M. Gubbens‐Stibbe et al. · Anesthesiology · 1999 · 58 citations

Rectal bioavailability of lidocaine in rats: Absence of significant first-pass elimination

Albertus G. de Boer, D. D. Breimer, J. Pronk et al. · Journal of Pharmaceutical Sciences · 1980 · 42 citations

Medicine, Physiology, Significant First-pass Elimination +7