Raquel L. Arribas

New Dual Small Molecules for Alzheimer’s Disease Therapy Combining Histamine H₃ Receptor (H3R) Antagonism and Calcium Channels Blockade with Additional Cholinesterase Inhibition

R.S. Malek, Raquel L. Arribas, Alejandra Palomino‐Antolín et al. · Journal of Medicinal Chemistry · 2019 · 42 citations · Full text

(±)-<b>BIGI-3h</b>: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer’s Disease

Lhassane Ismaïli, Julie Monnin, Adeline Etiévant et al. · ACS Chemical Neuroscience · 2021 · 33 citations · Full text

Gramine Derivatives Targeting Ca²⁺ Channels and Ser/Thr Phosphatases: A New Dual Strategy for the Treatment of Neurodegenerative Diseases

Rocío Lajarín-Cuesta, Carmen Nanclares, Juan-Alberto Arranz-Tagarro et al. · Journal of Medicinal Chemistry · 2016 · 30 citations · Full text

Multitarget Approach, Chemical Biology, Synaptic Signaling +21

Polycyclic maleimide-based derivatives as first dual modulators of neuronal calcium channels and GSK-3β for Alzheimer's disease treatment

Alessandra Bisi, Raquel L. Arribas, Matteo Micucci et al. · European Journal of Medicinal Chemistry · 2018 · 26 citations · Full text

Neurodegenerative Diseases, Disease Treatment, Alzheimer's Disease +10

Design and synthesis of multipotent 3-aminomethylindoles and 7-azaindoles with enhanced protein phosphatase 2A-activating profile and neuroprotection

Rocío Lajarín-Cuesta, Raquel L. Arribas, Carmen Nanclares et al. · European Journal of Medicinal Chemistry · 2018 · 17 citations · Full text

Medicinal Chemistry, Multipotent 3-Aminomethylindoles, Biochemistry +6