Kim G.M. Savelkouls

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

Kasper M.A. Rouschop, Twan van den Beucken, Ludwig J. Dubois et al. · Journal of Clinical Investigation · 2009 · 802 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

Marianne Koritzinsky, Michaël G. Magagnin, Twan van den Beucken et al. · The EMBO Journal · 2006 · 364 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Autophagy is required during cycling hypoxia to lower production of reactive oxygen species

Kasper M.A. Rouschop, Chantal H.M.A. Ramaekers, Marco B.E. Schaaf et al. · Radiotherapy and Oncology · 2009 · 139 citations

Life Sciences, Biology, Cell Biology +14

Hypoxia-induced Expression of Carbonic Anhydrase 9 Is Dependent on the Unfolded Protein Response

Twan van den Beucken, Marianne Koritzinsky, Hanneke E.C. Niessen et al. · Journal of Biological Chemistry · 2009 · 72 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Phosphorylation of eIF2α is required for mRNA translation inhibition and survival during moderate hypoxia

Marianne Koritzinsky, Kasper M.A. Rouschop, Twan van den Beucken et al. · Radiotherapy and Oncology · 2007 · 55 citations

Life Sciences, Cell Biology, Molecular Biology +14