Twan van den Beucken

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

Kasper M.A. Rouschop, Twan van den Beucken, Ludwig J. Dubois et al. · Journal of Clinical Investigation · 2009 · 802 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

Marianne Koritzinsky, Michaël G. Magagnin, Twan van den Beucken et al. · The EMBO Journal · 2006 · 364 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER

Twan van den Beucken, Elizabeth Koch, Kenneth C. Chu et al. · Nature Communications · 2014 · 232 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS

Kasper M.A. Rouschop, Ludwig J. Dubois, Tom G. Keulers et al. · Proceedings of the National Academy of Sciences · 2013 · 209 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Hypoxia-mediated downregulation of miRNA biogenesis promotes tumour progression

Rajesha Rupaimoole, Sherry Y. Wu, Sunila Pradeep et al. · Nature Communications · 2014 · 185 citations · Full text

Medicine, Cancer Biology, Molecular Biology +14