Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases

Richard L. Frock, Jiazhi Hu, Robin M. Meyers, +3

Nature Biotechnology

Genome-wide Translocation Sequencing Reveals Mechanisms of Chromosome Breaks and Rearrangements in B Cells

Roberto Chiarle, Yu Zhang, Richard L. Frock, +12

Cell

ChromatinGenome InstabilityGeneticsB CellsChromosome Biology +6

A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation

Brett Johnson, Ryan T. Nitta, Richard L. Frock, +5

Proceedings of the National Academy of Sciences

Retinoblastoma ProteinA-type LaminsCell ProliferationCell CycleTumor Biology +15

Detecting DNA double-stranded breaks in mammalian genomes by linear amplification–mediated high-throughput genome-wide translocation sequencing

Jiazhi Hu, Robin M. Meyers, Junchao Dong, +3

Nature Protocols

Genome InstabilityDna SequencingNext-generation SequencingGeneticsMolecular Biology +5

Lamin A/C and emerin are critical for skeletal muscle satellite cell differentiation

Richard L. Frock, Brian A. Kudlow, Angela Evans, +3

Genes & Development

Dystroglycan is required for polarizing the epithelial cells and the oocyte in <i>Drosophila</i>

Wu-Min Deng, Martina Schneider, Richard L. Frock, +4

Development

Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes

Jiazhi Hu, Yu Zhang, Lijuan Zhao, +6

Cell

ImmunogeneticsSignal TransductionGeneticsReceptor (Biochemistry)Molecular Biology +6

Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease

Annalisa Lattanzi, Joab Camarena, Premanjali Lahiri, +20

Science Translational Medicine

Mechanism of tandem duplication formation in BRCA1-mutant cells

Nicholas A. Willis, Richard L. Frock, Francesca Menghi, +7

Nature

Genome InstabilityGeneticsDna ReplicationMolecular GeneticsCell Cycle +4

PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line

Vipul Kumar, Frederick W. Alt, Richard L. Frock

Proceedings of the National Academy of Sciences